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AI-Driven Solutions for Immunotherapy

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Immunity by design

Dive into a world where advanced computational immunology meets precision medicine. Discover tools that revolutionize immunotherapy, drive scientific breakthroughs, and bring therapeutic solutions closer than ever. Explore our comprehensive suite of AI-powered platforms, designed to address your unique needs in vaccine design, off-target toxicity prediction, and TCR optimization.
 
Let's reshape the future of immunology together. Start your journey now - scroll down to learn more.

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Empowering Your Immunology Research

Unleash the full potential of your work in immunology with our tailored solutions. Discover cutting-edge tools specifically designed to navigate the complexities of immunopeptidomics, manage off-target toxicity, and optimize TCR-suite applications. Each platform equips you with the advanced capabilities needed to accelerate your research, enhance accuracy, and propel your scientific breakthroughs. Explore our offerings below.

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Precision peptide identification

ARDentify platform (incl. ARDisplay models) enables the precise identification of peptides presented via HLA molecules on the cell surface. This system delivers results significantly surpassing those of standard methods.

Excellently suited for target identification in both vaccine design and TCR-T cell therapies, ARDentify is a key tool in advancing your immunology research.

✔ Experimentally validated

Innovative cross-reactivity solutions

ARDitox platform identifies cross-reactive epitopes, which are often impractical and expensive to find using traditional approaches (e.g. using X-scan).

Embrace the future of immunotherapy with our advanced, patent-pending (EP22461636) technology, ensuring an unprecedented level of precision and efficiency in managing off-target toxicity.

✔ Experimentally validated
✔ Ongoing collaboration with Michael Platten's group (DKFZ)

Transformative TCR optimization

We are working on a TCRopt module to help maximize the therapeutic potential of TCRs while reducing the risk of off-target events.

Integrating ARDentify, ARDitox, and the TCR suite, we've created a robust database of over 4000 T-cell hits  from healthy donors and cancer patients for pHLA therapeutic targets. The future of immunotherapy is here

✔ Validation in progress
✔ Ongoing collaboration with Michael Platten's group (DKFZ)

Design multi-epitope peptide-based vaccines with Artificial Intelligence

Learn about our technology, Ardigen's ARDesign platform, based on cutting-edge computational immunology and machine learning and supported by experimentally-generated datasets. The platform enables the compilation of the ranked list of peptide antigens for the vaccine composition.

Optimize T-cell Therapies with Advanced Computational Tools

Get insights from the latest single-cell methodologies and how our suite of advanced computational tools can enhance your TCR discovery process. Learn from our case study where we employed a multiplexed and high-throughput approach to select clinically relevant tumor targets and build a database of novel target-specific TCR sequences.

 

At Ardigen, we're at the forefront of innovative solutions, revolutionizing immunotherapy development. Our advanced technologies span multiple areas, from computational immunology and artificial intelligence to structural biology and bioinformatics. These cutting-edge methods enable us to address key challenges and provide tailored solutions in the dynamic field of immunotherapy.

Immunology has seen significant advancements through the application of machine learning (ML) and artificial intelligence (AI). In the context of immune profiling and vaccine discovery, these advanced computational methods have brought about transformative changes, personalizing and fine-tuning therapeutic strategies. Our unique approach combines immunoinformatics and AI to facilitate antigen prediction, immune biomarker discovery, and immunogenomics research, leading to enhanced vaccine development and precision immunotherapy.

Our immunotherapy development further extends into the domain of immuno-oncology data analysis and immuno-peptidomics. We utilize bioinformatics to create predictive models, offering a comprehensive understanding of complex immunological data and opening new avenues in immunomics research.

Our advanced solutions also find application in autoimmunity research, where AI aids in immune response analysis. Moreover, we're developing tools like the TCR-T suite to help design and optimize T-cell therapies, ensuring a more effective immune response.

At Ardigen, our commitment to pioneering research and technology is aimed at shaping the future of immunology and therapeutic interventions. We're excited to push the boundaries of AI in precision immunotherapy, bioinformatics in immunology, and personalized immunotherapy.